Gene information
Official symbol EGLN3
Official full name egl-9 family hypoxia inducible factor 3
Gene type protein-coding gene
Chromosome14q13.1
Alias symbolPHD3; HIFPH3
Resources
Entrez Gene 112399
HGNC HGNC:14661
Ensembl ENSG00000129521
Vega OTTHUMG00000029498
UCSC uc001wsa.5
GO terms: 15 records
GO Description Category LogP Number of genes Detail
GO:0001666 response to hypoxia GO Biological Processes -40.6131384 77 More
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process GO Biological Processes -5.45408545 14 More
GO:0010950 positive regulation of endopeptidase activity GO Biological Processes -13.2452311 34 More
GO:0010952 positive regulation of peptidase activity GO Biological Processes -14.1524623 37 More
GO:0031406 carboxylic acid binding GO Molecular Functions -5.96500660 23 More
GO:0036293 response to decreased oxygen levels GO Biological Processes -40.9544531 79 More
GO:0036294 cellular response to decreased oxygen levels GO Biological Processes -14.5279047 32 More
GO:0043177 organic acid binding GO Molecular Functions -5.71225789 20 More
GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process GO Biological Processes -14.7594418 39 More
GO:0043523 regulation of neuron apoptotic process GO Biological Processes -14.5388618 39 More
GO:0051345 positive regulation of hydrolase activity GO Biological Processes -19.7369783 79 More
GO:0070482 response to oxygen levels GO Biological Processes -40.7566635 82 More
GO:0071453 cellular response to oxygen levels GO Biological Processes -14.8173809 34 More
GO:0071456 cellular response to hypoxia GO Biological Processes -14.4449186 31 More
GO:2000116 regulation of cysteine-type endopeptidase activity GO Biological Processes -14.4496812 41 More
Drug-Gene interaction
view
Related drugs: 2 records
Drug name Interaction type Source PMID View
daprodustat inhibitor ChemblInteractions view
roxadustat inhibitor TdgClinicalTrialChemblInteractions view
Related study: 1 record
Molecular factor Omics type Application Objective MI type Reference
cg16785755 hypermethylation epigenomics myocardial infarction[diagnosis] myocardial infarction Rask-Andersen M et al. Hum Mol Genet. 2016
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